Brad Hyman, MD, PhD

  • Director, Massachusetts Alzheimer's Disease Research Center, Massachusetts General Hospital
  • John B. Penney Professor of Neurology, Harvard Medical School

Bradley T. Hyman, M.D., Ph.D., is the Director of the Massachusetts Alzheimer’s Disease Research Center at MGH and the John B. Penney, Jr. Professor of Neurology at Harvard Medical School. His clinical career is devoted towards the care of patients with dementia. His research laboratory is pursuing research in Alzheimer’s disease, and other neurodegenerative diseases, with a goal of understanding the neuropathophysiologic and genetic factors that underlie dementia. Hyman is author of over 600 papers.

Dr. Hyman’s laboratory is developing methods to examine clinical-pathological correlates and biomarkers in AD, as well as animal and cell models to explore the natural history of the diseases. A recent focus has been the use of advanced microscopy methods – including multiphoton microscopy for in vivo imaging of plaques, tangles, and synuclein aggregates, as well as FRET methods to detect protein-protein interactions and protein conformation.

Dr. Hyman received a B.A. in chemistry from Northwestern University and a Ph.D. in Biochemistry and M.D. from the University of Iowa, where he also did residency in neurology and fellowships in Behavioral neurology and neuropathology. He joined the faculty at Harvard Medical School in 1989. Dr. Hyman has received the Potamkin Prize, a Metropolitan Life Award, a Brookdale Foundation fellowship, an Alzheimer Association Faculty Scholar Award, an Alzheimer Association Pioneer Award, and a National Institute on Aging Merit Award. He is a member of the National Academy of Medicine.

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